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— 2021—

Boonyalai N, Thamnurak C, Sai-Ngam P, et al. Plasmodium falciparum phenotypic and genotypic resistance profile during the emergence of Piperaquine resistance in Northeastern Thailand. Sci Rep. 2021;11:13419. https://doi.org/10.1038/s41598-021-92735-6   

 

Brocato RL, Altamura LA, Carey BD, et al. Comparison of transcriptional responses between pathogenic and nonpathogenic hantavirus infections in Syrian hamsters using NanoString. PLoS Negl Trop Dis. 2021;15(8):e0009592. https://doi.org/10.1371/journal.pntd.0009592  

 

Brocato RL, Kwilas SA, Josleyn MD, et al. Small animal jet injection technique results in enhanced immunogenicity of hantavirus DNA vaccines. Vaccine. 2021;39(7):1101-1110. https://doi.org/10.1016/j.vaccine.2021.01.002  

 

Brocato RL, Kwilas SA, Kim RK, et al. Protective efficacy of a SARS-CoV-2 DNA vaccine in wild-type and immunosuppressed Syrian hamsters. NPJ Vaccines. 2021;6(1):16. https://doi.org/10.1038/s41541-020-00279-z  

 

Cai Y, Yu S, Chi X, Radoshitzky SR, Kuhn JH, Berger EA. An immunotoxin targeting Ebola virus glycoprotein inhibits Ebola virus production from infected cells. PLoS One. 2021;16(1):e0245024. https://doi.org/10.1371/journal.pone.0245024  

 

Cai Y, Yu S, Fang Y, et al. Development and characterization of a cDNA-launch recombinant Simian hemorrhagic fever virus expressing enhanced green fluorescent protein: ORF 2b' is not required for in vitro virus replication. Viruses. 2021;13(4):632. https://doi.org/10.3390/v13040632  

 

Chapman NS, Zhao H, Kose N, et al. Potent neutralization of Rift Valley fever virus by human monoclonal antibodies through fusion inhibition. Proc Natl Acad Sci U S A. 2021;118(14):e2025642118. https://doi.org/10.1073/pnas.2025642118  

 

Chen Y, Toth EA, Ruan B, et al. Engineering subtilisin proteases that specifically degrade active RAS. Commun Biol. 2021;4(1):299. https://doi.org/10.1038/s42003-021-01818-7  

 

Chiang CY, Zhong Y, Ward MD, et al. Proteomic analysis of non-human primate peripheral blood mononuclear cells during Burkholderia mallei infection reveals a role of ezrin in glanders pathogenesis. Front Microbiol. 2021;12:625211. https://doi.org/10.3389/fmicb.2021.625211  

 

Clayton NP, Jain A, Halasohoris SA, et al. In vitro and in vivo characterization of tebipenem (tbp), an orally active carbapenem, against biothreat pathogens. Antimicrob Agents Chemother. 2021;65(5):e02385-20. https://doi.org/10.1128/aac.02385-20   

 

Cote CK, Biryukov SS, Klimko CP, et al. Protection elicited by attenuated live Yersinia pestis vaccine strains against lethal infection with virulent Y. pestis. Vaccines (Basel). 2021;9(2):161. https://doi.org/10.3390/vaccines9020161  

 

Cote CK, Weidner JM, Klimko C, et al. Biological validation of a chemical effluent decontamination system. Appl Biosaf. 2021;26(1):23-32. https://doi.org/10.1089/apb.21.937967

 

Crooks CM, Weiler AM, Rybarczyk SL, et al. African-lineage Zika virus replication dynamics and maternal-fetal interface infection in pregnant rhesus macaques. J Virol. 2021;95(16):e0222020. https://doi.org/10.1128/jvi.02220-20  

 

Engdahl TB, Kuzmina NA, Ronk AJ, et al. Broad and potently neutralizing monoclonal antibodies isolated from human survivors of New World hantavirus infection. Cell Rep. 2021;35(5):109086. https://doi.org/10.1016/j.celrep.2021.109086  

 

Evans TS, Myat TW, Hom NS, et al. Seroepidemiologic survey of Crimean-Congo hemorrhagic fever virus in logging communities, Myanmar. Emerg Infect Dis. 2021;27(6):1709-1713. https://doi.org/10.3201/eid2706.203223

 

Fall G, Diallo D, Soumaila H, et al. First detection of the West Nile virus Koutango lineage in sandflies in Niger. Pathogens. 2021;10(3):257. https://doi.org/10.3390/pathogens10030257  

 

Fels JM, Maurer DP, Herbert AS, et al. Protective neutralizing antibodies from human survivors of Crimean-Congo hemorrhagic fever. Cell. 2021;184(13):3486-3501.e21. https://doi.org/10.1016/j.cell.2021.05.001  

 

Frick OM, Livingston VA, Whitehouse CA, et al. The natural history of aerosolized Francisella tularensis infection in cynomolgus macaques. Pathogens. 2021;10(5):597. https://doi.org/10.3390/pathogens10050597  

 

Golden JW, Zeng X, Cline CR, et al. Human convalescent plasma protects K18-hACE2 mice against severe respiratory disease. J Gen Virol. 2021;102(5):001599. https://doi.org/10.1099/jgv.0.001599  

 

Grund ME, Soo JC, Cote CK, Berisio R, Lukomski S. Thinking outside the bug: targeting outer membrane proteins for Burkholderia vaccines. Cells. 2021;10(3):495. https://doi.org/10.3390/cells10030495  

 

Guito JC, Prescott JB, Arnold CE, et al. Asymptomatic infection of Marburg virus reservoir bats is explained by a strategy of immunoprotective disease tolerance. Curr Biol. 2021;31(2):257-270.e255. https://doi.org/10.1016/j.cub.2020.10.015  

 

Gupta Y, Maciorowski D, Zak SE, et al. Heparin: A simplistic repurposing to prevent SARS-CoV-2 transmission in light of its in-vitro nanomolar efficacy. Int J Biol Macromol. 2021;183:203-212. https://doi.org/10.1016/j.ijbiomac.2021.04.148  

 

Haddow AD, Clarke SC. Inaccuracies in Google's health-based knowledge panels perpetuate widespread misconceptions involving infectious disease transmission. Am J Trop Med Hyg. 2021;104(6):2293-2297. https://doi.org/10.4269/ajtmh.21-0216  

 

Haddow AD, Rowland TE, Norris SL, et al. No evidence of rVSV-Ebola virus vaccine replication or dissemination in the sand fly Phlebotomus papatasi. Am J Trop Med Hyg. 2021;104(3):1093-1095. https://doi.org/10.4269/ajtmh.20-0951  

 

Haddow AD, Watt TR, Bloomfield HA, Fetterer DP, Harbourt DE. Modeling the stability of SARS-CoV-2 on personal protective equipment (PPE). Am J Trop Med Hyg. 2020;104(2):549-551. https://doi.org/10.4269/ajtmh.20-1508  

 

Herring S, Oda JM, Wagoner J, et al. Inhibition of arenaviruses by combinations of orally available approved drugs. Antimicrob Agents Chemother. 2021;65(4):e01146-20. https://doi.org/10.1128/aac.01146-20  

 

Herring S, Oda JM, Wagoner J, et al. Erratum for Herring et al., "Inhibition of arenaviruses by combinations of orally available approved drugs". Antimicrob Agents Chemother. 2021;65(6):e00653-21. https://doi.org/10.1128/aac.00653-21  

 

Hollidge BS, Cohen CA, Akuoku Frimpong J, Badger CV, Dye JM, Schmaljohn CS. Toll-like receptor 4 mediates blood-brain barrier permeability and disease in C3H mice during Venezuelan equine encephalitis virus infection. Virulence. 2021;12(1):430-443. https://doi.org/10.1080/21505594.2020.1870834  

 

Jelacic TM, Ribot WJ, Tobery SA, Chabot DJ, Friedlander AM. Poly-γ-glutamic acid encapsulation of Bacillus anthracis inhibits human dendritic cell responses. Immunohorizons. 2021;5(2):81-89. https://doi.org/10.4049/immunohorizons.2100004  

 

Jiang J, Ramos SJ, Bangalore P, et al. Multivalent DNA vaccines as a strategy to combat multiple concurrent epidemics: mosquito-borne and hemorrhagic fever viruses. Viruses. 2021;13(3):382. https://doi.org/10.3390/v13030382

 

Johnston SC, Ricks KM, Jay A, et al. Development of a coronavirus disease 2019 nonhuman primate model using airborne exposure. PLoS One. 2021;16(2):e0246366. https://doi.org/10.1371/journal.pone.0246366  

 

Keasey SL, Zhao BM, Ulrich RG, Suh MJ. Proteomic analysis of antibiotic susceptibility in Enterobacteriaceae. Methods Mol Biol. 2021;2296:381-392. https://doi.org/10.1007/978-1-0716-1358-0_22  

 

Kijek TM, Bozue JA, Panchal RG, Litosh VA, Woodard RW, Ahmed SA. A direct spectropolarimetric assay of arabinose 5-phosphate isomerase. Anal Biochem. 2021;622:114116. https://doi.org/10.1016/j.ab.2021.114116  

 

Kinganda-Lusamaki E, Black A, Mukadi DB, et al. Integration of genomic sequencing into the response to the Ebola virus outbreak in Nord Kivu, Democratic Republic of the Congo. Nat Med. 2021;27(4):710-716. https://doi.org/10.1038/s41591-021-01302-z  

 

Kuehnert PA, Stefan CP, Badger CV, Ricks KM. Crimean-Congo hemorrhagic fever virus (CCHFV): a silent but widespread threat. Curr Trop Med Rep. 2021:1-7. https://doi.org/10.1007/s40475-021-00235-4  

 

Larson PA, Bartlett ML, Garcia K, et al. Genomic features of humoral immunity support tolerance model in Egyptian rousette bats. Cell Rep. 2021;35(7):109140. https://doi.org/10.1016/j.celrep.2021.109140  

 

Li T, Chung HK, Pireku PK, et al. Rapid high-throughput whole-genome sequencing of SARS-CoV-2 by using one-step reverse transcription-PCR amplification with an integrated microfluidic system and next-generation sequencing. J Clin Microbiol. 2021;59(5):e02784-20. https://doi.org/10.1128/jcm.02784-20  

 

Lin JT, Waltmann A, Moser KA, et al. Selection of cytochrome b mutants is rare among Plasmodium falciparum patients failing treatment with Atovaquone-Proguanil in Cambodia. Antimicrob Agents Chemother. 2021;65(3):e01249-20. https://doi.org/10.1128/aac.01249-20  

 

Liu JL, Webb EM, Zabetakis D, et al. Stabilization of a broadly neutralizing anti-chikungunya virus single domain antibody. Front Med (Lausanne). 2021;8:626028. https://doi.org/10.3389/fmed.2021.626028  

 

Luban J, Sattler RA, Mühlberger E, et al. The DHODH inhibitor PTC299 arrests SARS-CoV-2 replication and suppresses induction of inflammatory cytokines. Virus Res. 2021;292:198246. https://doi.org/10.1016/j.virusres.2020.198246  

 

Maccio U, Zinkernagel AS, Shambat SM, et al. SARS-CoV-2 leads to a small vessel endotheliitis in the heart. EBioMedicine. 2021;63:103182. https://doi.org/10.1016/j.ebiom.2020.103182  

 

Martchenko Shilman M, Bartolo G, Alameh S, et al. In vivo activity of repurposed Amodiaquine as a host-targeting therapy for the treatment of anthrax. ACS Infect Dis. 2021;7(8):2176-2191. https://doi.org/10.1021/acsinfecdis.1c00190  

 

Montgomery VA, Lindsey CY, Smith LA, Webb RP. Development of an o-pthalaldehyde (OPA) assay to measure protein content in Ricin Vaccine E. coli (RVEc™). Vaccine. 2021;39(3):564-570. https://doi.org/10.1016/j.vaccine.2020.12.008  

 

Mou S, Jenkins CC, Okaro U, Dhummakupt ES, Mach PM, DeShazer D. The Burkholderia pseudomallei hmqA-G locus mediates competitive fitness against environmental gram-positive bacteria. Microbiol Spectr. 2021:e0010221. https://doi.org/10.1128/spectrum.00102-21  

 

Newman CM, Tarantal AF, Martinez ML, et al. Early embryonic loss following intravaginal Zika virus challenge in rhesus macaques. Front Immunol. 2021;12:686437. https://doi.org/10.3389/fimmu.2021.686437

 

Niemuth NA, Fallacara D, Triplett CA, et al. Natural history of disease in cynomolgus monkeys exposed to Ebola virus Kikwit strain demonstrates the reliability of this non-human primate model for Ebola virus disease. PLoS One. 2021;16(7):e0252874. https://doi.org/10.1371/journal.pone.0252874  

 

Okaro U, George S, Anderson B. What is in a cat scratch? Growth of Bartonella henselae in a biofilm. Microorganisms. 2021;9(4):835. https://doi.org/10.3390/microorganisms9040835  

 

Papp-Wallace KM, Shapiro AB, Becka SA, et al. In vitro antibacterial activity and in vivo efficacy of sulbactam-durlobactam against pathogenic Burkholderia species. Antimicrob Agents Chemother. 2021;65(3):e01930-20. https://doi.org/10.1128/aac.01930-20  

 

Paquin-Proulx D, Gunn BM, Alrubayyi A, et al. Associations between antibody Fc-mediated effector functions and long-term sequelae in Ebola virus survivors. Front Immunol. 2021;12:682120. https://doi.org/10.3389/fimmu.2021.682120  

 

Pierson BC, Cardile AP, Okwesili AC, et al. Safety and immunogenicity of an inactivated eastern equine encephalitis virus vaccine. Vaccine. 2021;39(20):2780-2790. https://doi.org/10.1016/j.vaccine.2021.03.030  

 

Pinky L, Burke CW, Russell CJ, Smith AM. Quantifying dose-, strain-, and tissue-specific kinetics of parainfluenza virus infection. PLoS Comput Biol. 2021;17(8):e1009299. https://doi.org/10.1371/journal.pcbi.1009299  

 

Rappazzo CG, Tse LV, Kaku CI, et al. Broad and potent activity against SARS-like viruses by an engineered human monoclonal antibody. Science. 2021;371(6531):823-829. https://doi.org/10.1126/science.abf4830  

 

Saikh KU. MyD88 and beyond: a perspective on MyD88-targeted therapeutic approach for modulation of host immunity. Immunol Res. 2021;69(2):117-128. https://doi.org/10.1007/s12026-021-09188-2  

 

Stefan CP, Arnold CE, Shoemaker CJ, et al. Transcriptomic analysis reveals host miRNAs correlated with immune gene dysregulation during fatal disease progression in the Ebola virus cynomolgus macaque disease model. Microorganisms. 2021;9(3):665. https://doi.org/10.3390/microorganisms9030665  

 

Strange DP, Jiyarom B, Sadri-Ardekani H, et al. Paracrine IFN response limits ZIKV infection in human sertoli cells. Front Microbiol. 2021;12:667146. https://doi.org/10.3389/fmicb.2021.667146  

 

Suschak JJ, Golden JW, Fitzpatrick CJ, et al. A CCHFV DNA vaccine protects against heterologous challenge and establishes GP38 as immunorelevant in mice. NPJ Vaccines. 2021;6(1):31. https://doi.org/10.1038/s41541-021-00293-9  

 

Trefry JC, Rossi FD, Accardi MV, et al. The utilization of advance telemetry to investigate critical physiological parameters including electroencephalography in cynomolgus macaques following aerosol challenge with eastern equine encephalitis virus. PLoS Negl Trop Dis. 2021;15(6):e0009424. https://doi.org/10.1371/journal.pntd.0009424

 

Trevino SR, Dankmeyer JL, Fetterer DP, et al. Comparative virulence of three different strains of Burkholderia pseudomallei in an aerosol non-human primate model. PLoS Negl Trop Dis. 2021;15(2):e0009125. https://doi.org/10.1371/journal.pntd.0009125  

 

Turell MJ, Dohm DJ, Fernandez R, Klein TA. Vector competence of Peruvian mosquitoes for two Orthobunyaviruses isolated from mosquitoes captured in Peru. J Med Entomol. 2021;58(3):1384-1388. https://doi.org/10.1093/jme/tjaa252  

 

Vaughan JA, Hinson J, Andrews ES, Turell MJ. Pre-existing microfilarial infections of American robins (Passeriformes: Turdidae) and common grackles (Passeriformes: Icteridae) have limited impact on enhancing dissemination of West Nile virus in Culex pipiens mosquitoes (Diptera: Culicidae). J Med Entomol. 2021;58(3):1389-1397. https://doi.org/10.1093/jme/tjaa261  

 

Vietri NJ, Tobery SA, Chabot DJ, et al. Clindamycin protects nonhuman primates against inhalational anthrax but does not enhance reduction of circulating toxin levels when combined with ciprofloxacin. J Infect Dis. 2021;223(2):319-325. https://doi.org/10.1093/infdis/jiaa365  

 

Voss WN, Hou YJ, Johnson NV, et al. Prevalent, protective, and convergent IgG recognition of SARS-CoV-2 non-RBD spike epitopes. Science. 2021;372(6546):1108-1112. https://doi.org/10.1126/science.abg5268  

 

Waag DM, Chance TB, Trevino SR, et al. Comparison of three non-human primate aerosol models for glanders, caused by Burkholderia mallei. Microb Pathog. 2021;155:104919. https://doi.org/10.1016/j.micpath.2021.104919  

 

Wang Y, Howell KA, Brannan J, et al. Prominent neutralizing antibody response targeting the Ebolavirus glycoprotein subunit interface elicited by immunization. J Virol. 2021;95(8):e01907-20. https://doi.org/10.1128/jvi.01907-20  

 

White LE, Holland RL, Scruggs JL. What is your diagnosis? A scrotal lesion in a cynomolgus macaque. Vet Clin Pathol. 2021;50(2):302-304. https://doi.org/10.1111/vcp.12961